NF5280M4 on Windows Server 2008 R2: Slow USB 3.0 and Intermittent Input
Symptoms and source diagnosis
In the reported NF5280M4 case after Windows Server 2008 R2 installation, an external USB 3.0 disk copied at about 20 MB/s, and USB keyboard/mouse input intermittently stopped responding or lost pointer movement. The source attributes the problem to the USB driver and calls for an updated platform driver.
The source calls this an issue with the system’s built-in USB 3.0 driver. Microsoft documents its native USB 3.0 stack as a Windows 8 / Windows Server 2012 addition. For this older platform, check the installed controller and the vendor-supported Server 2008 R2 driver rather than assuming a later Windows inbox stack is present.
1. Review the BIOS xHCI setting
The source uses Chipset → PCH Configuration → USB Configuration → xHCI Mode → Auto. Other listed ports remain Enabled. Plan any BIOS change and reboot for the actual server; the screenshot records the intended setting, not a change performed here:

With that controller exposed, the source shows a Universal Serial Bus (USB) Controller under Other devices with a yellow driver-warning icon:

2. Install the supported platform driver
Obtain the correct USB 3.0 driver for this server, controller and Windows Server 2008 R2 from the supplied server media or its official support channel. The source names USB3.0 for windows2008R2 but provides no exact package version or post-install Device Manager result. Do not substitute a package merely because another server uses USB 3.0.
3. Review the target disk’s removal policy
The source’s navigation is Computer → Device Manager → Disk drives → the intended disk → Properties → Policies. Its first policy picture uses a VMware virtual SCSI disk as a navigation illustration; it does not show the NF5280M4 external disk under a performance test:

For the intended removable device, the source selects Better performance. The next picture uses a ChipBank SD/MM Reader USB Device as another illustrative device. This policy enables write caching and requires using Safely Remove Hardware before disconnecting so pending writes can finish:

The source reports a copy rate above 100 MB/s after its changes, without a benchmark capture or enough detail to guarantee that rate on another disk. Confirm the controller driver and retest the actual transfer workload and input devices; a caching-policy selection alone is not proof of link speed or resolution of intermittent input.